无水葡萄糖在生产时需要什么样的干燥方式？
来源：http://www.jnjdbc.com 日期：2019-06-24 发布人：admin
葡萄糖是生物体内新陈代谢不可短少的营养物质，它的氧化反响放出的热量是人类生命活动所需能量的重要来源，在食品、医药工业上可直接运用，在工业上还大量用葡萄糖为原料合成维生素C。其主要制剂产品是大输液和高渗中针，由于输液和中针的特殊给药途径，原料的质量就显得特别重要。特别是热源反响、杂质含量、异物等，假如没有保证，都可能对患者形成极大的伤害。无水葡萄糖是消费输液或中针的换代产品，美国及日本等国度作为注射用的葡萄糖都请求用无水葡萄糖，并在国度药典中反映，如日本药方规则葡萄糖注射液仅以无水糖为原料。无水葡萄糖是一水葡萄糖的更新换代产品，与一水葡萄糖相比产品具有无热源反响、杂质含量少、纯度高等优点。
Glucose is an indispensable nutrient for metabolism in organisms. The heat released by its oxidation reaction is an important source of energy for human life activities. It can be directly used in food and pharmaceutical industries. In industry, it is also used as raw material to synthesize vitamin C. Its main preparation products are large transfusion and hypertonic medium needle. Because of the special route of transfusion and medium needle administration, the quality of raw materials is particularly important. Especially the heat source response, impurity content, foreign body and so on, if not guaranteed, may cause great harm to patients. Anhydrous glucose is a replacement product for infusion or mid-needle. In the United States and Japan countries, anhydrous glucose is required for injection, and it is reflected in the national pharmacopoeia, such as the Japanese Pharmacopoeia Rules that glucose injection only takes anhydrous sugar as raw material. Anhydrous glucose is a renewal product of monohydrate glucose. Compared with monohydrate glucose, the product has the advantages of no heat source, less impurity content and high purity.
在医药行业，应用无水葡萄糖制成的葡萄糖注射液、葡萄糖氯化钠注射液，可用于因某些缘由进食减少或不能进食时补充热能；关于低血症、饥饿性酮症、失水等有良好的医疗效果。无水葡萄糖的消费多采用双酶法以淀粉乳为原料，经过液化、糖化、除渣、脱色、离交、蒸发、结晶、别离等精制处置得到一水葡萄糖，后经溶糖、脱色、煮糖、别离、枯燥及包装工序得到无水葡萄糖。无水葡萄糖由于不含结晶水，大大减少了杂质及微生物的引入。无水葡萄糖消费行业中，产品枯燥是关键一步。无水葡萄糖在煮糖结晶、别离终了之后，物料水分普通在2%左右，枯燥设备效率上下，直接影响着整个消费的效率和产质量量，枯燥器性能是保证产质量量和节约能源的关键环节。
In the pharmaceutical industry, glucose injection and sodium chloride injection made of anhydrous glucose can be used to supplement heat energy when food is reduced or cannot be eaten for some reasons, and have good medical effects on hypoxemia, hunger ketosis and dehydration. The consumption of anhydrous glucose is mostly made from starch milk by double enzymatic method. After liquefaction, saccharification, slag removal, decolorization, separation, evaporation, crystallization, separation and other refined disposal, anhydrous glucose is obtained by dissolving, decolorizing, boiling, separating, drying and packaging processes. Because anhydrous glucose does not contain crystalline water, it greatly reduces the introduction of impurities and microorganisms. In anhydrous glucose consumption industry, product dryness is the key step. When anhydrous glucose is boiled and crystallized and separated, the moisture content of the material is generally about 2%. The efficiency of the drying equipment directly affects the efficiency of the whole consumption and the quality of the production. The performance of the dryer is the key link to ensure the quality of the production and save energy.
目前，无水葡萄糖消费企业产品的枯燥以流化床为主要枯燥设备，流化床具有维护工作量小、毛病率低、维护烦琐、运转牢靠等诸多优点，但是，回混床设备操作不易控制、沸腾效果不好、单位面积产量低，同比，流化床枯燥效率低，不利于大范围消费，产品单耗较高。
At present, fluidized bed is the main drying equipment in anhydrous glucose consumption enterprises. Fluidized bed has many advantages, such as small maintenance workload, low defect rate, cumbersome maintenance, reliable operation, etc. However, the back mixing bed equipment is not easy to control, boiling effect is not good, unit area output is low, compared with the same period, the drying efficiency of fluidized bed is low, which is not conducive to large-scale consumption and unit consumption of products. Higher.
风机是无水葡萄糖消费枯燥过程中更重要的辅助设备之一，而更初应用于此类枯燥系统的引风机、送风机均采用电机工频恒速运转方式，再经过入口风门挡板节流调理风量来到达自动控制流化床体内压力的目的，其弊端是无法有效控制电机，无论系统负荷有无变化，电机均处于工频运转形式。这既形成了大量电能的糜费，也降低了电机的寿命，另一方面多数厂家仍采用传统的控制办法即经过继电器控制，这种控制方式存在着启动电流大，运转平安牢靠性差、能源糜费等问题。枯燥过程中，在保证枯燥送风的干净度的同时，将少量水分更有效率的去除掉，如何在保证枯燥效果的同时停止，在消费质量跟踪过程中还发现，无水葡萄糖废品入库后，物料温度有上升的现象，极不利于贮存，也是搅扰当前消费厂家的一个问题。
Fan is one of the most important auxiliary equipments in the drying process of anhydrous glucose consumption. Initially, the induction fans and the draft fans used in this kind of drying system all adopt the constant speed operation mode of motor power frequency, and then through the throttling of the inlet valve baffle to regulate the air flow to achieve the purpose of automatic control of the internal pressure of fluidized bed. The disadvantage is that the motor can not be effectively controlled, regardless of the change of the load of the system. The motors are in the form of power frequency operation. On the other hand, most manufacturers still adopt the traditional control method, i.e. through relay control. This control method has many problems, such as large starting current, poor safety and reliability of operation, energy wastage, and so on. In the process of dryness, while ensuring the cleanliness of dry air supply, removing a small amount of moisture more efficiently. How to stop energy saving while ensuring the dryness effect? In the process of consumption quality tracking, it is also found that after the anhydrous glucose waste is put into storage, the material temperature rises, which is not conducive to storage, and is also a problem that disturbs the current consumer manufacturers.
创造内容本适用新型的目的在于，克制现有技术的缺乏，提供了无水葡萄糖枯燥设备，一段升温枯燥，二 段持续降温的工艺安装，防止了因连续枯燥形成的物料温度高，废品容易变色结块的现象。
The purpose of creating new content is to restrain the shortage of existing technology, provide anhydrous glucose drying equipment, install one stage of heating and drying, two stages of continuous cooling process, and prevent the high temperature of materials formed by continuous drying and the phenomenon of discoloration and caking of waste products.
另外，在回混床底部设计装置搅拌器，当发现回混床内的压力升高，物料液位上升时，开启搅拌，保证物料的沸腾效果。
In addition, an agitator is designed at the bottom of the back mixing bed. When the pressure in the back mixing bed rises and the liquid level of the material rises, the agitator is turned on to ensure the boiling effect of the material.
普通无水葡萄糖消费企业均采用一级流化床系统，枯燥气体经过旋风别离器后直接排入大气。枯燥气体温度高，气体中含有大量糖粉，经过旋风别离器后仍携带有较多的糖粉，直接排入大气中，形成了严重的环境污染，同时，大量糖粉流失，使产品收率降低，形成较严重的糜费，不利于消费。
The ordinary anhydrous glucose consumption enterprises adopt the first-stage fluidized bed system, and the dry gas is directly discharged into the atmosphere after the cyclone separator. Dry gas has high temperature and contains a large amount of sugar powder. After cyclone separator, it still carries more sugar powder, which is directly discharged into the atmosphere, resulting in serious environmental pollution. At the same time, a large amount of sugar powder is lost, which reduces the yield of the product and forms a serious waste, which is not conducive to consumption.
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